American Society for Clinical Pathology (ASCP) Histotechnologist Practice Test

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What is the primary function of mast cells in connective tissues?

  1. Immune response modulation

  2. Storage of lipids

  3. Production of collagen

  4. Maintenance of blood flow

The correct answer is: Immune response modulation

Mast cells play a crucial role in the immune response within connective tissues. They are primarily known for their involvement in allergic reactions and responses to pathogens. These cells contain granules filled with histamine and other mediators that are released during an immune response, leading to various effects such as vasodilation, increased permeability of blood vessels, and recruitment of other immune cells to the site of inflammation. This function is vital for initiating and regulating the body’s response to injury or infection. While other options highlight important functions in biological systems, they do not pertain to the primary role of mast cells. Storage of lipids is primarily a function of adipocytes, and collagen production is predominantly the job of fibroblasts. Moreover, maintenance of blood flow involves several factors including vasculature and circulatory cells, which are not directly related to mast cells. Thus, immune response modulation is a key and defining function of mast cells in connective tissues.

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